David Carling (UK)
Eric Clauser (France), Jacques E. Dumont (Belgium), Michael Freissmuth (Austria), Stefan Offermanns (Germany), Bernard Payrastre (France), Stéphane Schurmans (Belgium), Giancarlo Vecchio (Italy), Pierre De Meyts (Denmark) and Claudia Wellbrock (UK)

·       Central control of energy homeostasis

·       Metabolism and Cell growth

·      Metabolism and Cancer

One of the fundamental properties of all living cells is the ability to maintain proper regulation of energy metabolism. In higher organisms, complex systems have evolved to ensure that energy intake matches energy expenditure. Perturbation of this system has serious implications for survival. In humans, an obvious consequence of dysfunctional energy metabolism is the development of obesity and type 2 diabetes (aspects of the metabolic syndrome) that are increasing at an alarming rate. Less obvious, perhaps, is that energy metabolism underlies cell growth and proliferation, and in cancer deranged energy metabolism is central to the unrestricted growth of cancer cells. This symposium will cover the latest aspects of research examining the role of energy metabolism in health and disease. Topics will cover the regulation of energy metabolism in peripheral tissues (including the beneficial role of exercise in skeletal muscle), the central control of energy metabolism (with talks on the hypothalamic control of appetite and energy expenditure), metabolism and cell growth (including talks on the role of the AMPK and mTOR/S6K pathways) and the role of metabolism in cancer (with talks on regulation of glycolysis and the role of HIF). The Symposium will bring together experts in these fields ensuring a lively and stimulating environment for discussion.

The Symposium will bring together scientists studying the role and regulation of energy metabolism in health and disease. In addition to established PI’s, the Symposium aims to attract researchers at an early stage in their career and to actively promote their participation in the meeting. One way this will be achieved is to hold two dedicated Poster sessions (all participants will be encouraged to present Posters). In addition, 3 Posters from PhD students or early-stage post-doctoral fellows will be chosen for Oral Presentations (from the Abstracts submitted). A major emphasis will be to encourage discussion from all participants during the meeting

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Location and Getting There

Mont Sainte-Odile is approximately 50 km from Strasbourg (40 km from Strasbourg airport) and 115 km from Basel. Direct flights to Strasbourg are available from a number of European cities including Bordeaux, Brussels, Copenhagen, Lille, Lisbon, London (City airport), Lyon, Madrid, Marseille, Nice, Paris and Prague. Strasbourg is well served by train (connections to UK via Paris and the Eurostar). Coaches to and from Strasbourg (train station and airport) will be provided for participants. In addition, Basel EuroAirport serves flights to many European destinations